Foreign policy has differed at various points in its history from influential actors in the international system. With Donald Trump's arrival at the White House, US foreign policy vis-à-vis different countries has changed dramatically, with differences in Obama's foreign policy. Trump's emphasis on economic variables, given the background of his economic activities, did not enable him to use interactive approaches to resolve tensions and disputes with some governments in the Middle East on the one hand and resolve conflicts between governments in the Middle East on the other. Power, security, and balance of power in the Middle East were considered the most central concepts in the international arena of his foreign policy vis-à-vis the Middle East during his presidency. Leaving Bridgewater is one of the most significant examples of the Trump administration's distance from the interactive and peaceful approaches in the Middle East. In the present paper, the components of economic hegemony, Islamic divergence under the pretext of terrorism, unilateralism, and increased deterrence in Trump's foreign policy toward the Middle East are examined in a descriptive-analytical approach based on Kenneth Waltz's realism approach.